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- Abprazole 700® Omeprazole Granules and Spier® 700mg Omeprazole Tablets direct from manufacturer, no script required.
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Our Products
Gastric Ulcer Treatments
Anthelmintics
Anti-Inflammatories
Probiotics
Hello from Us B+M

Hi, We're Bernadette (left) and Michelle (right). We are the good ladies behind this business and web site, and the people that will look after you and your order - from start to finish.
We run a 100% transparent and trustworthy business and look forward to processing your orders. Please do not hesitate to contact us with your questions.
Omeprazole Direct
Omeprazole Direct offers ulcer treatment medication for horses and humans. Our medication comes in tablets, paste and powder form and a variety of dosages. Our prices are the cheapest on the web!

Spier® has rebranded and is now packaged under the new brand name: |
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- Same great products, including an exciting new range (and more to come!)
- Same manufacturing, management and customer service
- Same affordable quality
- Professional, new packaging

Abprazole 700® Omeprazole GRANULES
Equine Omeprazole
What is Equine Gastric Ulcer Syndrome (EGUS)
In horses, as well as in humans, it's a wound in the lining of the stomach caused by acid. In humans we call it heartburn or gastric reflux and can efficiently describe the symptoms allowing our usdical professionals to recommend medicines .. the most popular being Prilosec (Omeprazole).
Our horses can't tell us they have a problem, but they can sure show us!
(See symptoms on our Frequently Asked Questions page)
Facts about Stomach Ulcers in Horses
- Up to 93% of racehorses gets stomach ulcers, regardless of age
- Almost 60% of other performance horses have ulcers
- Up to 57% of foals have stomach ulcers, particularly during the early months
- 50% of horses with ulcers show no outward signs of gastrointestinal disease
What is Omeprazole?
Omeprazole is in a class of drugs called proton pump inhibitors (PPI) which block the production of acid by the stomach. Proton pump inhibitors are used for the treatment of conditions such as ulcers and Equine Gastro esophageal Ulcer syndrome (EGUS) which are caused by stomach acid. Omeprazole, like other proton-pump inhibitors, blocks the enzyme in the wall of the stomach that produces acid. By blocking the enzyme, the production of acid is decreased, and this allows the stomach and esophagus to heal. Omeprazole OTC has minimal side effects in humans and has been approved for sale without a prescription. Click here for more detail on Omeprazole.
Administration
The Omeprazole API (Active Pharmacological Ingredient) is highly acid labile and moisture sensitive, and hence oral formulations are Enteric Coated. But such formulations are expensive, time consuming to manufacture & require elaborate technology; also such formulations are moisture sensitive. Their complexity makes it impossible to manufacture effective compounds outside very specialized laboratory facilities.
Omeprazole powders and some pastes available afford the active ingredient no protection (enteric coating) from the acid environment of the stomach, so by the time it reaches the intestine, the active ingredient has been destroyed!
Equine Omeprazole is available in two forms ... tablets (700mg) and granules (700mg).
Abprazole 700® Granules
Abprazole 700® granules are Enteric Coated in that they are coated with a cellulose polymer. The objective is for the cellulose to protect the active ingredient from the acid in the stomach, allowing the granules to pass into the intestine where they then dissolve and go to work on the proton pumps producing the acid. The cellulose will not dissolve in acid media but does dissolve in neutral media. The granules are easy to administer mixed with a treat or apple.
Spier® Tablets
Spier® tablets are also Enteric Coated in that they are coated with a cellulose polymer. The objective is for the cellulose to protect the active ingredient from the acid in the stomach, allowing the tablet to pass into the intestine where they then dissolves and goes to work on the proton pumps producing the acid. The cellulose will not dissolve in acid media but does dissolve in neutral media.
If the tablets were to dissolve in the stomach, stomach acid would render the Omeprazole ineffective. Thus, crushing tablets will greatly reduce their efficiency.
What causes Equine Gastric Ulcer Syndrome?
Horses secrete acid even when they are not eating, and for the most part, their stomachs are designed to withstand the secretions. The lining on the top portion of the stomach has minimal protection. But the bottom portion, which resembles the lining of the human stomach, is glandular in structure and has elaborate means of withstanding acid secretions.
A horse's penchant for grazing is natural self-protection against ulcers. When a horse grazes all day, the roughage he consumes absorbs a considerable amount of digestive acid, keeping the level within the stomach low. In addition, a horse's saliva has an acid-neutralizing effect. As a result, the amount of acid that accumulates in a horse's stomach declines when he's eating and increases when he's not - sometimes to a potentially injurious level - which manifests itself in the form of gastric ulcers.
Problems arise when you bring a horse into stall confinement and then provide large quantities of concentrate - whether it be grain or pelleted feed. Grain or pelleted feed increases the level of a hormone known as gastrin, which is released by the stomach and acts as a stimulant for acid secretion. Then after eating his grain, the horse might stand for some time without eating hay, and all the while he is producing acid.
A second significant contributor to the development of lesions in a horse's stomach is the intensity of his training. For reasons not yet fully understood, a program that demands more of a horse may predispose him to ulcers.
Other risk factors include stress, transportation, intermittent feeding, racing, illness and management changes.
How do I check if my horse is suffering from EGUS?
A positive diagnosis can be made with the use of an endoscope which allows the veterinarian to insert an optical tube down the horse's throat and into the stomach and to inspect the lining for ulceration. However, most veterinary practices do not have such an expensive piece of equipment and diagnosis is usually suspected by the symptoms and confirmed by a positive reaction to treatment with Omeprazole. Improvement is usually noticed within 24 hours.
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Customer Testimonial
Mixed the Omeprazole Granules with Corn syrup and added to feed worked for my fussy eater. Didnt dissolve..I will be back again to order more. Horse Colic no more - Best Wishes Fussy Filly! - Laurie Kentucky USA





